Prevention of Future Deaths reports · 2019

Brenda McWilliams

Regulation 28 report to prevent future deaths, reference 2019-0406, written 29 Nov 2019. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report29 Nov 2019
Reference2019-0406
DeceasedBrenda McWilliams
CoronerPeter Sigee
Coroner areaManchester North
CategoryHospital Death (Clinical Procedures and medical management) related deaths
Organisation namedPennine Acute Hospitals NHS Trust
Sourcejudiciary.uk record · original PDF
Responses publishednone published

The report

Text extracted from the PDF text layer. Reproduced verbatim, including the scan's own layout.

REGULATION 28: REPORT TO PREVENT FUTURE DEATHS (1) 

REGULATION 28 REPORT TO PREVENT FUTURE DEATHS 

THIS REPORT IS BEING SENT TO: 

 The Chief Executive, National Institute for Health & Care Excellence (“NICE”), 10 Spring Gardens, 
London SW1A 2BU  

1 

CORONER 

I am Peter Sigee, Assistant Coroner for the Coroner area of Manchester North 

2 

CORONER’S LEGAL POWERS 

I make this report under paragraph 7, Schedule 5, of the Coroner’s and Justice Act 2009 and Regulations 28 
and 29 of the Coroners (Investigations) Regulations 2013 

3 

INVESTIGATION and INQUEST 

 On the 15th January 2019 the Senior Coroner for the Coroner Area of Manchester North commenced 
an investigation into the death of Mrs Brenda McWilliams. The investigation concluded at the end of 
the inquest on 15th November 2019. The inquest determined that Mrs McWilliams died from natural 
causes, namely 1(a) Pulmonary Thromboembolism, 1(b) Deep Vein Thrombosis of the Leg Vein, 1(c) 
Poor Mobility, 2 Alzheimer’s Disease.  

4 

CIRCUMSTANCES OF DEATH 

 Mrs Brenda McWilliams died at the Royal Oldham Hospital on 3rd January 2019, aged 75 years.  
Mrs McWilliams had been diagnosed as suffering from Alzheimer's disease in October 2014.  
On 12th December 2018 Mrs McWilliams was unable to get out of bed, she was taken to hospital by 
ambulance and admitted; the hospital suspected that she may have developed delirium secondary 
to an infection.  
Mrs McWilliams remained immobile and she was assessed as being at high risk of venous 
thromboembolism (''VTE''). The hospital recognised that if a VTE developed then this was likely to be 
serious, even life-threatening. Whilst in hospital, Mrs McWilliams was given a daily injection of 
medication to minimise the risk of VTE.  
The hospital assessed Mrs McWilliams as fit for discharge to a residential care home on a short term 
basis while efforts were made to mobilise her.  
On 21st December 2018 Mrs McWilliams was discharged by the hospital and she moved to a 
residential care home. Mrs McWilliams remained immobile and the hospital recognised that: (1) at 
the time of discharge she remained at high risk of VTE; and (2) if this developed it was likely to be 
serious, even life-threatening. The hospital did not prescribe or recommend the use of medication to 
minimise the risk of VTE after discharge.  
  Whilst in the care home, Mrs McWilliams remained immobile and her condition continued 
  to deteriorate. Mrs McWilliams’ GP prescribed antibiotics for a suspected infection but no treatment            
was given to minimise the risk of VTE at this time.  

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 On  2nd  January  2019  Mrs  McWilliams'  physical  condition  deteriorated  and  she  was  admitted  to 
hospital. Doctors considered that it was likely that Mrs McWilliams was suffering from sepsis and she 
was treated accordingly. Mrs McWilliams continued to deteriorate and she died on 3rd January 2019.  
from  a  pulmonary 
Post  mortem  examination  revealed 
thromboembolism  caused  by  a  deep  vein  thrombosis  of  the  leg  vein  which  was  caused  by  her 
immobility and that her death was contributed to by Alzheimer's disease.  

that  Mrs  McWilliams  had  died 

It is likely that the symptoms that the symptoms that were thought to be due to sepsis were in fact caused 
by the pulmonary thromboembolism. 

5 

CORONER’S CONCERNS 

During the course of the inquest the evidence revealed matters giving rise to concern. In my opinion there is 
a risk that future deaths will occur unless action is taken. In the circumstances it is my statutory duty to 
report to you.  
The MATTERS OF CONCERN are as follows:-  
I am concerned that the various medical practitioners who attended upon Mrs McWilliams did not consider 
continuing prescribing Mrs McWilliams medication to minimise the risk of VTE after her discharge from 
hospital on 21st December 2018 despite recognising that:  
(1) Mrs McWilliams remained at high risk of VTE and the consequence of such an event was likely to be very 
serious, even life threatening;  
(2) it had been deemed appropriate to administer medication to Mrs McWilliams by means of daily 
injections whilst in hospital; and  
(3) there were no other suitable means identified and/or adopted to minimise this risk.  
I understand that NICE has published the following guidance:  

  Guideline NG89 “VTE in over 16s: reducing the risk of hospital-acquired deep vein thrombosis 

or pulmonary embolism”  

  Quality Standard QS29 “VTE in adults: diagnosis and management”  

I was told that QS29 does not include recommendations for the prevention of VTE.  
The evidence that I heard suggested that medical practitioners have interpreted the NICE guidance as saying 
that it is not necessary/appropriate to prescribe medication to minimise the VTE risk for patients who are 
living in the community unless they have been discharged from hospital with short term immobility (for 
example with their leg in a cast following a fracture).  
Whilst I recognise that the decision to prescribe medication is a multi-factoral clinical decision I am 
concerned that the evidence I heard suggests that some patients living in the community who are at high 
risk of VTE (who may not have been admitted to hospital whilst at high risk of VTE) are not being assessed 
and treated with medication to minimise the risk of VTE, which if it develops can be a life-threatening 
condition.  

6 

ACTION SHOULD BE TAKEN 

In my opinion action should be taken to prevent future deaths and I believe each of you respectively 
have the power to take such action. 

7 

YOUR RESPONSE 

You are under a duty to respond to this report within 56 days of the date of this report, namely 24th 
January 2020. I, the Coroner, may extend the period.  
Your  response  must  contain  details  of  action  taken  or  proposed  to  be  taken,  setting  out  the 
timetable for action. Otherwise you must explain why no action is proposed. 

 
 
 
 
 
 
 
 
 
 
 
 8 

COPIES and PUBLICATION 

I have sent a copy of my report to the Chief Coroner and to the following Interested Persons namely 
Mrs McWilliams’ family and the Pennine Acute Hospitals NHS Trust.  

I am also under a duty to send the Chief Coroner a copy of your response.  

The Chief Coroner may publish either or both in a complete or redacted or summary from. He may send a 
copy  of  this  report  to  any  person  who  he  believes  may  find  it  useful  or  of  interest.  You  may  make 
representations to me  the  coroner  at  the  time  of your  response,  about  the  release or  the  publication of 
your response by the Chief Coroner. . 

9 

Date:          29th November 2019                                                                   Signed:

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