Prevention of Future Deaths reports · 2014

George Stone

Regulation 28 report to prevent future deaths, reference 2014-0379, written 20 Aug 2014. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report20 Aug 2014
Reference2014-0379
DeceasedGeorge Stone
CoronerDavid Horsley
Coroner areaPortsmouth & South East Hampshire
CategoryCommunity health care and emergency services related deaths
Sourcejudiciary.uk record · original PDF
Responses publishednone published

The report

Text extracted from the PDF text layer. Reproduced verbatim, including the scan's own layout.

ANNEX A 

REGULATION 28:  REPORT TO PREVENT FUTURE DEATHS (1) 

NOTE: This form is to be used after an inquest. 

REGULATION 28 REPORT TO PREVENT FUTURE DEATHS 

THIS REPORT IS BEING SENT TO: 

Ms S. Horsfall 
Chief Executive 
National Patient Safety Agency 
4-8 Maple Street 
London W1T 5HD 

1 

CORONER 

I am David Clark Horsley, senior coroner, for the coroner area of Portsmouth and South 
East Hampshire. 

2 

CORONER’S LEGAL POWERS 

I make this report under paragraph 7, Schedule 5, of the Coroners and Justice Act 2009 
and regulations 28 and 29 of the Coroners (Investigations) Regulations 2013. 

3 

INVESTIGATION and INQUEST 

On 22nd November 2012 I commenced an investigation into the death of George 
Douglas Stone, aged 37. The investigation concluded at the end of the inquest on 16th 
August 2013. The conclusion of the inquest was that the medical cause of George 
Stone's death was Yew Tree Leaf Intoxication and he had taken his own life whilst 
suffering from a long term depressive disorder. 

4 

CIRCUMSTANCES OF THE DEATH 

George Stone suffered from long term depressive illness. In August 2012 he was 
prescribed Venlafaxine which caused him to suffer a grand mal seizure on 6th 
September 2012. This in turn led to an exacerbation of his depressive illness and he 
ended his own life on 19th November 2012. 

5 

CORONER’S CONCERNS 

During the course of the inquest the evidence revealed matters giving rise to concern. In 
my opinion there is a risk that future deaths will occur unless action is taken. In the 
circumstances it is my statutory duty to report to you. 

The MATTERS OF CONCERN are as follows.  –  

I was told in evidence at the Inquest that a side effect of Venlafaxine and similar 
antidepressants is seizures and that although this is rare, these seizures can be very 
severe - as was the case with George Stone. I was also told that the NPSA issues 
national guidelines for the warnings practitioners must give their patients who are 
prescribed these sorts of antidepressants but the risk of patients suffering a severe 
seizure is not included in the guidelines at the present time. 

1

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 6 

ACTION SHOULD BE TAKEN 

In my opinion action should be taken to prevent future deaths by consideration of 
changes to the guidelines for prescribing Venlafaxine and similar antidepressants to 
include a specific warning to patients about the risks of their suffering severe seizures 
whilst taking these medications. I believe your organisation has the power to take such 
action.  

7 

YOUR RESPONSE 

You are under a duty to respond to this report within 56 days of the date of this report, 
namely by 15th October 2014. I, the coroner, may extend the period. 

Your response must contain details of action taken or proposed to be taken, setting out 
the timetable for action. Otherwise you must explain why no action is proposed. 

8 

COPIES and PUBLICATION 

I have sent a copy of my report to the Chief Coroner and to the following Interested 
Persons: Mr Stone's parents, 
Coroners Society of England and Wales who may find it useful or of interest. 

 I have also sent it to the 

I am also under a duty to send the Chief Coroner a copy of your response.  

The Chief Coroner may publish either or both in a complete or redacted or summary 
form. He may send a copy of this report to any person who he believes may find it useful 
or of interest. You may make representations to me, the coroner, at the time of your 
response, about the release or the publication of your response by the Chief Coroner. 

9 

20th August 2014                                              David Clark Horsley 

2

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