Prevention of Future Deaths reports · 2019

Nathan Cooke

Regulation 28 report to prevent future deaths, reference 2019-0125, written 17 Apr 2019. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report17 Apr 2019
Reference2019-0125
DeceasedNathan Cooke
CoronerCaroline Sumeray
Coroner areaIsle of Wight
CategoryHospital Death (Clinical Procedures and medical management) related deaths
Organisation namedIsle of Wight NHS Trust
Sourcejudiciary.uk record · original PDF
Responses publishednone published

The report

Text extracted from the PDF text layer. Reproduced verbatim, including the scan's own layout.

REGULATION 28:  REPORT TO PREVENT FUTURE DEATHS 

THIS REPORT IS BEING SENT TO: 

1. 

2. 

 Practice Manager, The Dower House Surgery, 27 Pyle 

Street, Newport, Isle of Wight, PO30 1JW. 

 Executive Director of Quality and Nursing, Hampshire and 

Isle of Wight Partnership of Clinical Commissioning Groups, c/o 
CommCen Building, Fort Southwick, James Callaghan Drive, Fareham 
PO17 6AR 

1 

CORONER 

I am Caroline Sarah Sumeray, Senior Coroner for the Coroner Area of the Isle of Wight. 

2 

CORONER’S LEGAL POWERS 

I make this report under paragraph 7, Schedule 5, of the Coroners and Justice Act 2009 

and regulations 28 and 29 of the Coroners (Investigations) Regulations 2013. 

3 

INVESTIGATION and INQUEST 

On  1st  March  2018  I  commenced  an  investigation  into  the  death  of  Nathan  John 

COOKE, aged 36. The investigation concluded at the end of the inquest on 15th April 

2019. The conclusion of the inquest was “Drug Related”. 

The medical cause of death was found to be: 

 1a Cardio-Respiratory Failure 

 1b Severe Central Nervous System Depression 

 1c Methadone and Clomipramine Overdose 

  II 

4 

CIRCUMSTANCES OF THE DEATH 

1)  Nathan John COOKE was born on 4th January 1982. At the time of his death he 

was 36 years old and was unemployed. 

2)  Nathan John COOKE was found dead by his mother at 16.30 hours at his home 

address of 

, Isle of Wight. He had last been seen 

by his mother when she had left the address that morning, but he was asleep at 

that point. 

1 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 3)  Mr COOKE had been prescribed a number of medications for his mental health 

and previous drug addiction issues, which included Methadone (an opioid drug 

which can be used for pain relief in some circumstances but is more commonly 

used  as  replacement 

therapy 

for  heroin  addiction  or  withdrawal)  and 

Clomipramine  (a  tricyclic  antidepressant  drug  where  adverse  reactions  to 

excessive  doses  may  cause  cardiac  arrhythmias,  convulsions  and  central 

nervous system depression.) 

4)  Good  practice  dictates  that  when  a  patient  is  being  prescribed  Clomipramine, 

they  should  be  monitored  by  ECG  heart  trace  for  the  abnormal  heart  rhythm 

known as “QTc prolongation” which is a risk factor in sudden cardiac death. 

5)  Mr  COOKE  had  been  monitored  in  October  2017  and  was  found  to  have  an 

abnormal  reading  with  a  QTc  prolongation  at  488  which  could  have  been 

caused  by  the  Methadone  and  Clomipromine.  The  guidance  says  that  where 

there  is a QTc of greater than  440, but less than 500, consideration  should be 

given  to  reducing  the  dose  of  the  medication  or  switching  to  a  drug  of  lower 

effect, and repeating the ECG. 

6)  Mr COOKE and his mother were notified of this ECG concern, in particular the 

increased risk of potential heart arrhythmia and death. 

7)  Mr  COOKE  supplemented  his  prescription  medication  with  illicit  medication 

which had not been prescribed to him. 

8)  Mr COOKE was offered a number of appointments to attend for a further ECG – 

but  he  failed  to  attend  them  or  declined  to  have  the  screen  done  when  he 

attended  for  appointments.  Efforts  were  made  to  reduce  the  dosage  of  the 

medication which he was being prescribed, with variable results. 

9) 

It  was  acknowledged  by  the  Drugs  Worker  who  attended  Court  that  it  was 

important  to  convey  to  Mr  COOKE  (and  other  patients)  that  they  absolutely 

needed  to  have  a  further  ECG  scan  and  review  the  results  for  patient  safety. 

Whilst  it  was  possible  to  decline  to  provide  any  further  prescriptions  to  the 

patient  to  compel  them  to  attend  the  surgery  in  order  to  obtain  a  prescription, 

this  could  be  dangerous  as  it  might  precipitate  them  stopping  their  medication 

suddenly. 

10) Whilst it is not believed that Mr COOKE suffered a fatal cardiac arrhythmia as a 

result  of  taking  these  medications,  this  was  a  risk  factor  which  was  not 

adequately addressed in his clinical management. 

2 

 
 
 
 
 
 
 
 
 
 
 5 

CORONER’S CONCERNS 

During the course of the inquest the evidence revealed matters giving rise to concern. In 

my opinion there is a risk that future deaths will occur unless action is taken. In the 

circumstances it is my statutory duty to report to you. 

The MATTERS OF CONCERN are as follows:  –  

1. 

It was agreed that a more appropriate way to manage and control this situation 

whereby  a  patient  is  prescribed  medication  which  could  be  dangerous  to  their 

welfare without regular monitoring would be for the primary care practice to write 

to the patient, inviting them to attend for a review, and informing them that if they 

failed  to  attend  the  review  by  a  specified  date,  their  medication  would  be 

reduced and eventually stopped. The incentive and responsibility to comply with 

clinicians is thereby passed to the patient. 

6 

ACTION SHOULD BE TAKEN 

In my opinion action should be taken to prevent future deaths and I believe you and/or 
your organisation have the power to take such action.  

7 

YOUR RESPONSE 

You are under a duty to respond to this report within 56 days of the date of this report, 
namely by 5th June 2019. I, the Coroner, may extend the period. 

Your response must contain details of action taken or proposed to be taken, setting out 
the timetable for action. Otherwise you must explain why no action is proposed. 

8 

COPIES and PUBLICATION 

I  have  sent  a  copy  of  my  report  to  the  Chief  Coroner  and  to  the  following  Interested 
Persons: 

 and the Isle of Wight NHS Trust. 

I am also under a duty to send the Chief Coroner a copy of your response.  

The  Chief  Coroner  may  publish  either  or  both  in  a  complete  or  redacted  or  summary 
form. He may send a copy of this report to any person who he believes may find it useful 
or  of  interest.  You  may  make  representations  to  me,  the  Coroner,  at  the  time  of  your 
response, about the release or the publication of your response by the Chief Coroner. 

9 

H.M. Senior Coroner – Isle of Wight 
17th April 2019 

3

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