Prevention of Future Deaths reports · 2020

Kalila Griffiths

Regulation 28 report to prevent future deaths, reference 2020-0299, written 18 Dec 2020. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report18 Dec 2020
Reference2020-0299
DeceasedKalila Griffiths
CoronerNadia Persaud
Coroner areaEast London
CategoryHospital Death (Clinical Procedures and medical management) related deaths · Community health care · Other related deaths
Sourcejudiciary.uk record · original PDF
Responses published1

The report

Text extracted from the PDF text layer. Reproduced verbatim, including the scan's own layout.

MISS N PERSAUD 
SENIOR CORONER 

EAST LONDON 

Walthamstow Coroner's Court, Queens Road Walthamstow, E17 8QP 
Telephone 020 8496 5000 Email coroners@walthamforest.gov.uk 

REGULATION 28:  REPORT TO PREVENT FUTURE DEATHS (1) 

Ref: 

REGULATION 28 REPORT TO PREVENT FUTURE DEATHS 

THIS REPORT IS BEING SENT TO: 

1.

, Respiratory Lead, NHS England, Royal

Brompton Hospital, Sidney Street, London, SW3 6NB
Email: 

1 

CORONER 

I am Nadia Persaud senior coroner, for the coroner area of East London 

2 

CORONER’S LEGAL POWERS 

I make this report under paragraph 7, Schedule 5, of the Coroners and Justice Act 2009 
and Regulations 28 and 29 of the Coroners (Investigations) Regulations 2013. 
http://www.legislation.gov.uk/ukpga/2009/25/schedule/5/paragraph/7 
http://www.legislation.gov.uk/uksi/2013/1629/part/7/made 

3 

INVESTIGATION and INQUEST 

On 5th September 2019 I commenced an investigation into the death of Kalila Elizabeth 
Griffiths, age 22. The investigation concluded at the end of the inquest on the 14th 
December 2020. The conclusion of the inquest was a narrative conclusion: 

Kalila Griffiths died from natural causes.  Her death was however contributed to by a 
lack of recognition of the seriousness of the decline of her respiratory state in the 4 
weeks leading up to her death.  By the 19th January 2019 Kalila required a review by a 
respiratory physician.  Had such a review taken place, on the balance of probabilities, 
her death would have been avoided. 

4 

CIRCUMSTANCES OF THE DEATH 

Kalila Griffiths had complex medical history including, asthma, Ehlers-Danlos syndrome 

1 

 
 and postural tachycardia syndrome.  In December 2018 she developed shortness of 
breath. She attended her GP surgery on the 4th January 2019.  The GP prescribed 
medication for a chest infection and for asthma.  Despite this treatment, Kalila’s 
respiratory health deteriorated during January 2019 rendering her largely unable to 
mobilise.  She was confined to her bedroom for most of January 2019.  Kalila required at 
least four attendances at her GP practice and two attendances to A & E (6 and 19 
January). The second A&E attendance - 19th January 2019 - followed a life-threatening 
deterioration in her breathing.  Kalila had recorded an oxygen saturation of 74% prior to 
presentation at the hospital.  She had been unable to speak to the 111 operator and she 
could be heard with a continuous cough in the background.  Notwithstanding her poor 
clinical state, she was discharged from hospital without the required observation; clinical 
assessment and history gathering.  She required admission to hospital at this time, for 
assessment by a respiratory physician.  Had she received observation in hospital and 
assessment by a respiratory physician on the 19th January 2019, on the balance of 
probabilities her death would have been avoided.  Kalila passed away on the 1 February 
2019.  The direct cause of death was a pulmonary embolism.  Her asthma was found to 
have contributed to her death.   

Her medical management on the multiple presentations over a short space of time, 
appears to have centred largely on treating the immediate presentation as an isolated 
event.  Insufficient account was given to the risk of ongoing attacks and other 
complications arising.    

The Inquest heard that the general practice and the Trust involved in this case have 
taken a number of steps to improve the care provided to asthma patients.  The Inquest 
however heard from a number of witnesses that there are concerns about the care 
provided to asthma patients nationally. 

5 

CORONER’S CONCERNS 

During the course of the inquest the evidence revealed matters giving rise to concern. In 
my opinion there is a risk that future deaths could occur unless action is taken. In the 
circumstances it is my statutory duty to report to you. 

The MATTERS OF CONCERN are as follows:  

(1)  Factual and expert witnesses gave evidence that there are concerns about the 
management of asthma patients within the NHS as a whole. The National 
Review of Asthma Deaths (“NRAD”), was published in 2014.  This was five 
years before the care provided to Kalila and six years before the Inquest. 
Notwithstanding the length of time that has passed, the Inquest heard that 
eighteen of the nineteen recommendations set out in the NRAD report have not 
been implemented.  The recommendations of importance in this case were: 

  Patients with asthma must be referred to a specialist asthma service if 

they have required more than two courses of systemic corticosteroids in 
the previous twelve months.  

  Follow-up arrangements must be made after every attendance at an 
emergency department or out of hours’ service for an asthma attack.  

  Secondary care follow-up should be arranged after patients have 

attended the emergency department two or more times with an asthma 
attack in the previous twelve months.   

  Electronic surveillance of prescribing in primary care should be in place 

to pick up too many or too few preventer inhalers.   

(2)  Clinicians raised concerns in relation to the number of different guidelines 
relating to asthma (NICE Guidelines, BTS/SIGN Guidelines and GINA 
Guidelines).  It was noted that there are discrepancies between the guidelines.  
This makes it difficult for those general practitioners and emergency care 
practitioners who are providing care to patients. 

2 

 
 
 
 
 
 
 
 
 
 (3)  It was noted that it is not clear to healthcare professionals which guidelines 

should be used for the management of acute asthma attacks.  Many clinicians 
consider that the NICE guidelines can be used for the management of an acute 
asthma flare-up.  The Inquest heard that this is incorrect and that the BTS/SIGN 
guidelines should be used. 

(4)  The evidence revealed that further training is required for GPs and emergency 

departments in providing safe asthma care. 

6 

ACTION SHOULD BE TAKEN 

In my opinion action should be taken to prevent future deaths and I believe you have the 
power to take such action.  

7 

YOUR RESPONSE 

You are under a duty to respond to this report within 56 days of the date of this report, 
namely by 17 February 2021. I, the coroner, may extend the period. 

Your response must contain details of action taken or proposed to be taken, setting out 
the timetable for action. Otherwise you must explain why no action is proposed. 

8 

COPIES and PUBLICATION 

I have sent a copy of my report to the Chief Coroner and to the following Interested 
Persons: family of Kalila Griffiths, BHRUT NHS Trust, Fullwell Avenue Medical Practice. 
I have also sent it the CQC and Director of Public Health who may find it useful or of 
interest.  

I am also under a duty to send a copy of your response to the Chief Coroner and all 
interested persons who in my opinion should receive it.   

I may also send a copy of your response to any other person who I believe may find it 
useful or of interest.  

The Chief Coroner may publish either or both in a complete or redacted or summary 
form. He may send a copy of this report to any person who he believes may find it useful 
or of interest.  

You may make representations to me, the coroner, at the time of your response, about 
the release or the publication of your response. 

9 

18th December 2020                   SIGNED BY CORONER   

3

Responses

1 response published against this report on judiciary.uk. A response is a body's written reply to the coroner's concerns; publication is at the discretion of the Chief Coroner's office, so an absent response does not mean nobody replied.

Response from NHS England and NHS Improvement (PDF)
Ms Nadia Persaud 
Senior Coroner 

Walthamstow Coroners Court  
Queens Road 
Walthamstow 
London 
E17 8QP 

Dear Ms Nadia Persaud 

National Clinical Director for Respiratory Disease 

 Clinical Policy Unit        
Medical Directorate                             

16th February 2021 

Thank you for your Regulation 28 report, dated 18th December 2020, concerning the tragic 
death of Kalila Elizabeth Griffiths on 1st February 2019.  I would like to express my deep 
condolences to Kalila’s family. 

You have raised concerns regarding the care and follow-up leading to Kalila’s death and 
the general management of asthma patients in the NHS.   

NHS England published the NHS Long Term Plan1 in January 2019.  The plan has a clear 
commitment to improve the outcomes for those with a respiratory condition including 
asthma.  Since the publication of the Long Term Plan there is now a National Respiratory 
Programme working across a number of priority areas including the improvement of asthma 
outcomes. 

There have been significant improvements in asthma care since the publication of the 
National Review of Asthma Deaths in 2014.  Asthma deaths in younger people are falling, 
with under 65 year old deaths reducing by half in the last 15 years2.  As your report 
mentions there is still further improvements to be made. 

NHS England and NHS Improvement commission the National Asthma Audit Programme 
that provides data on a range of indicators to show improvements and opportunities in 
asthma outcomes. 

In response to your recommendations of the case I have outlined the work currently in 
progress that is contributing to the improved outcomes for people with asthma. 

Where people with asthma require specialist input this may include seeing a nurse or other 
healthcare professional with the competency and training to assess, treat and manage 
asthma.  This combined with monitoring of asthma exacerbations (within QOF) is the first 

1 https://www.longtermplan.nhs.uk/  
2https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/adhocs/005955asthmadeathsinenglandandw
ales2001to2015occurrences  

NHS England and NHS Improvement 

 
 
 
 
  
 
 
 
 
 
 
 
  
 
 
 step in ensuring that correct treatments and other interventions are administered in a timely 
manner.   

The British Thoracic Society (BTS) asthma discharge bundle3 describes five high impact 
actions to ensure the best clinical outcome for patients attending hospital with an acute 
asthma attack. The aim is to reduce the number of patients who are readmitted following 
discharge and to ensure that all aspects of the patient’s asthma care are considered.  The 
bundle includes: checking of medicines, inhaler technique, action plan, triggers for 
exacerbations and follow-up in the community within two working days and specialist care 
according to criteria within two weeks.  This is nationally recommended as best practice 
following hospital admission for an asthma attack. 

 (to be implemented in 2021) includes 

An update to the GP contract4 for 
an improved Quality Outcomes Framework (QOF) asthma domain: The content of the 
asthma review has been amended to incorporate aspects of care positively associated with 
better patient outcomes and self-management, including a review of inhaler technique, a 
record of the number of exacerbations in the previous 12 months, provision of a 
personalised asthma action plan and a validated measurement of asthma control to assess 
how the patient is managing their condition.  The asthma review is a key component in 
reducing the risk of asthma attacks and the need for acute admissions. 

The QOF for 2020/21 has been revised in response to COVID-19 to release capacity within 
general practice to focus efforts upon the identification and prioritisation of people at risk of 
poor health and those who experience health inequalities for proactive review including:  

•  Those most vulnerable to harm from COVID-19; evidence suggests that this 

includes patients from black and ethnic minority groups and those from the 20% 
most deprived neighbourhoods nationally.  

•  Those at risk of harm from poorly controlled long-term condition parameters 

(including asthma); and,   

•  Those with a history of missing annual reviews  

Data systems are already in place, further work is needed to ensure the data is analysed 
and used to inform patient treatment plans.  There is also the wider issue of medicines 
adherence, which is again part of the work of the Long Term Plan.  The Long Term Plan 
presents opportunities to ensure medicines optimisation and prescribing are integrated 
within the asthma care plan and annual reviews. 

The British Thoracic Society/SIGN and NICE are working collaboratively to produce a single 
guideline on the diagnosis and management of asthma.  A single guideline will ensure there 
is no confusion for healthcare professionals.  The ambition is to start production of the new 
guideline in 2021. 

3 https://www.brit-thoracic.org.uk/media/70102/bts-asthma-care-bundle-april-2016-v3.pdf  
4 https://www.england.nhs.uk/wp-content/uploads/2020/03/update-to-the-gp-contract-agreement-v2-updated.pdf  

 
 
 
 
 
 
 
 
 
 There are well established clinical guidelines for healthcare providers to follow, this includes 
both national and international guidelines: 

•  BTS/SIGN management of asthma5 
•  NICE guideline on asthma diagnosis monitoring and management6 
•  Global Initiative for Asthma7 

I would like to thank you for raising these important patient safety concerns, we will 
endeavour to do more to improve the outcomes for people with asthma to prevent such a 
tragedy in the future.  Please do not hesitate to contact me should you need any further 
information. 

Yours Sincerely 

National Clinical Director for Respiratory Disease.

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