Prevention of Future Deaths reports · 2021

Michele Duckworth

Regulation 28 report to prevent future deaths, reference 2021-0051, written 12 Feb 2021. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report12 Feb 2021
Reference2021-0051
DeceasedMichele Duckworth
CoronerSarah Murphy
Coroner areaStoke-on-Trent & North Staffordshire Coroner’s Court
CategoryHospital Death (Clinical Procedures and medical management) related deaths · Alcohol, drug and medication related deaths
Sourcejudiciary.uk record · original PDF
Responses publishednone published

The report

Text extracted from the PDF text layer. Reproduced verbatim, including the scan's own layout.

REGULATION 28 REPORT TO PREVENT FUTURE DEATHS 

THIS REPORT IS BEING SENT TO:  Chief Executive, Royal Stoke University Hospital, Newcastle Road, 
Stoke-on-Trent, ST4 6QG 
CORONER 

1 

I am Sarah Murphy HM Assistant Coroner for Stoke-on-Trent & North Staffordshire Coroner's Court 

2 

CORONER’S LEGAL POWERS 

I make this report under paragraph 7, Schedule 5, of the Coroners and Justice Act 2009 and regulations 
28 and 29 of the Coroners (Investigations) Regulations 2013. 
http://www.legislation.gov.uk/ukpga/2009/25/schedule/5/paragraph/7 
http://www.legislation.gov.uk/uksi/2013/1629/part/7/made 

3 

INVESTIGATION and INQUEST 

On 06/08/2020 I commenced an investigation into the death of Michele Brenda Duckworth, aged 57. The 
investigation concluded at the end of the inquest on 9th February 2021. The conclusion of the inquest 
was that death was due to natural causes against a background of complications from necessary 
immunosuppression therapy and long term urinary catheter resulting from a road traffic collision. 

4 

CIRCUMSTANCES OF THE DEATH 
The deceased had a medical history of paraplegia from a spinal cord injury due to a road traffic collision 
in 1984. This resulted in a requirement for intermittent self-catheterization and she suffered recurrent 
urinary tract infections. She had end stage renal failure and underwent a renal transplant in September 
2015 where she was then placed on immunosuppression therapy. She developed chronic diarrhoea and 
was under investigation at the Royal Stoke University Hospital, Stoke-on-Trent. She required two hospital 
admissions in October and December 2019 due to worsening of this condition. She was seen by the 
gastroenterology department on both hospital admissions and was referred for an outpatient 
appointment for a further investigation but the procedure  was cancelled because of her clinical 
condition. She had suffered weight loss and malnutrition and had been referred to the dietician during 
her hospital admissions where supplements were offered and trialled in October but NG feeding had 
been refused. She declined supplements in the December admission and had capacity to make this 
decision. She was admitted to the renal ward of the University hospital on the 10th February 2020 with 
profuse diarrhoea and low blood pressure.   She was treated with antibiotics, fluids and electrolyte 
replacement, blood transfusion, nutritional support and pancreatic enzymes supplements. She was 
clinically stable until the 21st February but then suddenly deteriorated on the 22nd February where she 
developed a temperature.  Previous rectal swabs had shown that she was colonised with ESBL but 
current rectal swabs were negative. She was treated for sepsis with Tazocin but Trust guidelines in these 
circumstances required a different antibiotic. This did not contribute to her subsequent death. She was 
transferred to the Intensive Care Unit but was not suitable for ventilation. Despite further treatment, she 
deteriorated and died at 3.10pm on the 23rd February 2020. A blood culture taken on the 22nd February 
found Escherichia Coli bacteraemia which was resistant to Tazocin. The result of the blood culture was 
not known until after she had passed away. A post mortem examination found that death was due to 
sepsis from Escherichia Coli bacteraemia of an unknown source.  
Sepsis (Escherichia Coli bacteraemia) of unknown source. 

5 

CORONER’S CONCERNS 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 During the course of the inquest the evidence revealed matters giving rise to concern. In my opinion 
there is a risk that future deaths will occur unless action is taken. In the circumstances it is my statutory 
duty to report to you. 

The MATTERS OF CONCERN are as follows.  –  

[BRIEF SUMMARY OF MATTERS OF CONCERN] 
(1) The deceased was incorrectly prescribed Tazocin when she was previously colonised with ESBL.  It was 
initially prescribed when she was on the renal ward and was continued when she was transferred to the 
Intensive Care Department. The antibiotic given in that context was not the antibiotic suggested in the 
trust guideline, and it was missed after several medical reviews. 

 
 
 
 
 
 
 
 
 
 6 

ACTION SHOULD BE TAKEN 

In my opinion action should be taken to prevent future deaths and I believe you and/or your organisation 
have the power to take such action.  

7 

YOUR RESPONSE 

You are under a duty to respond to this report within 56 days of the date of this report, namely by 21st 
April 2020. I, the coroner, may extend the period. 

Your response must contain details of action taken or proposed to be taken, setting out the timetable for 
action. Otherwise you must explain why no action is proposed. 

8 

COPIES and PUBLICATION 

I have sent a copy of my report to the Chief Coroner and to the following Interested Persons: 

1. 
2. 

Hospital) 

 (Son of deceased). 

 (Deputy Head of Legal Services, Legal Services Department, Royal Stoke University 

I am also under a duty to send the Chief Coroner a copy of your response and all interested persons who 
in my opinion should receive it. 

I may also send a copy of your response to any other person who I believe may find it useful or of 
interest. 

The Chief Coroner may publish either or both in a complete or redacted or summary form. He may send a 
copy of this report to any person who he believes may find it useful or of interest.  

You may make representations to me, the coroner, at the time of your response, about the release or the 
publication of your response. 

9 

12/02/2021 

Signature__________
Sarah Murphy HM Assistant Coroner Stoke-on-Trent & North Staffordshire Coroner's Court 

_______________

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