Prevention of Future Deaths reports · 2023

John James

Regulation 28 report to prevent future deaths, reference 2023-0242, written 11 Jul 2023. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report11 Jul 2023
Reference2023-0242
DeceasedJohn James
CoronerNadia Persaud
Coroner areaEast London
CategoryHospital Death (Clinical Procedures and medical management) related deaths
Organisation namedBarts Health NHS Trust
Sourcejudiciary.uk record · original PDF
Responses published1

The report

Text extracted from the PDF text layer. Reproduced verbatim, including the scan's own layout.

MISS N PERSAUD 
HIS MAJESTY’S CORONER 

EAST LONDON 

Walthamstow Coroner's Court, Queens Road Walthamstow, E17 8QP 

REGULATION 28:  REPORT TO PREVENT FUTURE DEATHS  

89792  

REGULATION 28 REPORT TO PREVENT FUTURE DEATHS 

THIS REPORT IS BEING SENT TO:  

, Group Chief Executive of Barts Health NHS Trust 

1 

CORONER 

I am Nadia Persaud, Area Coroner for the coroner area of East London 

2 

CORONER’S LEGAL POWERS 

I make this report under paragraph 7, Schedule 5, of the Coroners and Justice Act 2009 and 
Regulations 28 and 29 of the Coroners (Investigations) Regulations 2013. 
http://www.legislation.gov.uk/ukpga/2009/25/schedule/5/paragraph/7 
http://www.legislation.gov.uk/uksi/2013/1629/part/7/made 

3 

INVESTIGATION and INQUEST 

On 16 February 2023 I commenced an investigation into the death of Mr John Michael James. 
The investigation concluded at the end of the inquest on the 6 July 2023. The conclusion of the 
inquest was a narrative conclusion: 

Mr. James died as a result of a pulmonary embolism during the course of a lengthy hospital 
admission. He was at very high risk of developing a venous thromboembolism. There were three 
missed doses of anti-coagulation medication in the two weeks leading up to his death. 

4 

CIRCUMSTANCES OF THE DEATH 

1 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Mr. James was admitted to Whipps Cross Hospital on the 13 October 2022 and was found to be 
suffering from malnutrition and a bowel obstruction (later discovered to be due to an 
adenocarcinoma). He underwent surgery on 18 October 2022 to remove the tumour.  This was 
surgically uneventful. Post-operatively, he required a lengthy period of intensive care. On the 19 
December 2022 he was stepped down from intensive care to a ward. He was at a very high risk 
of developing a thromboembolism due to his cancer diagnosis, recent surgery, lengthy period in 
hospital and immobility. During the period of 9 to 15 January 2023 he refused his anti-
coagulation medication on three occasions. The reason for refusal is unclear and there is no 
documented evidence that the risk of non-compliance with the medication was explained to 
him or escalated to the medical team. On the 20 January 2023, Mr. James suffered from an 
acute deterioration in his health, culminating in a cardiac arrest. He passed away at Whipps 
Cross Hospital on the 21 January 2023 from a pulmonary embolism. The missing doses of 
anticoagulation during the two weeks leading up to his death is likely to have contributed to a 
degree, to the development of the pulmonary embolism.  
CORONER’S CONCERNS 

5 

During the course of the inquest the evidence revealed matters giving rise to concern. In my 
opinion there is a risk that future deaths could occur unless action is taken. In the circumstances 
it is my statutory duty to report to you. 

The MATTERS OF CONCERN are as follows:  

The refusal of anti-coagulation medication was not brought to the attention of medical staff.  
The administration of anti-coagulation medication to patients like Mr James, is vital for reducing 
the risk of a venous thrombo-embolism, a potentially life-threatening condition.  There is no 
electronic prompt/alert to highlight to the medical team when prescribed anticoagulation 
medication is not administered.    

The Trust’s internal investigator recognised that a fail-safe should be put in place within the 
electronic records, to ensure escalation to the medical team where doses of prescribed anti-
coagulation are not administered.  Such a measure could prevent similar deaths from occurring. 
It was considered that this measure could assist in preventing future deaths not just locally, but 
at a wider level.     

6 

ACTION SHOULD BE TAKEN 

In my opinion action should be taken to prevent future deaths and I believe you [AND/OR your 
organisation] have the power to take such action.  

7 

YOUR RESPONSE 

You are under a duty to respond to this report within 56 days of the date of this report, namely 
by 6 September 2023. I, the coroner, may extend the period. 

Your response must contain details of action taken or proposed to be taken, setting out the 
timetable for action. Otherwise, you must explain why no action is proposed. 

8 

COPIES and PUBLICATION 

I have sent a copy of my report to the Chief Coroner and to the family of Mr James. 
I have also sent a copy to the local Director of Public Health who may find it useful or of interest 
and to the CQC. 

I am also under a duty to send a copy of your response to the Chief Coroner and all interested 
persons who in my opinion should receive it.   

2 

 
 
 
 
 
 
   
 
 
 
 
 
 
 
 I may also send a copy of your response to any other person who I believe may find it useful or 
of interest.  

The Chief Coroner may publish either or both in a complete or redacted or summary form. He 
may send a copy of this report to any person who he believes may find it useful or of interest.  

You may make representations to me, the coroner, at the time of your response, about the 
release or the publication of your response. 

9 

11 July 2023         

3

Responses

1 response published against this report on judiciary.uk. A response is a body's written reply to the coroner's concerns; publication is at the discretion of the Chief Coroner's office, so an absent response does not mean nobody replied.

Response from Bart Health NHS Trust 1 (PDF)
Trust Executive Office 
Ground Floor 
Pathology and Pharmacy Building 
The Royal London Hospital 
80 Newark Street 
London E1 2ES 

Group Chief Medical Officer 

Date: 14th  September 2023 

Private & Confidential 
East London Coroners Court 
Queens Road 
Walthamstow 
London 
E17 8QP 

Dear HM Coroner, 

Thank  you  for  your  letter  dated  11th  July 2023  following  the  inquest  of  Mr  John  James 
detailing concerns  arising  from  the  evidence  presented  and  inviting  the  Trust  to  consider  the 
implementation of changes to reduce the risk of future harm or death. 

The Prevention of Future Death report has been reviewed at the Whipps Cross Hospital Board and 
Divisional Board to agree actions that will be adopted across the Barts Health group. 

Your concerns 

1.  The refusal of anti-coagulation medication was not  brought to the attention of medical staff. 
The administration of anti-coagulation medication to patients like Mr James, is vital for reducing 
the  risk  of  a  venous  thrombo-embolism,  a  potentially  life-threatening  condition.  There  is  no 
electronic  prompt/alert  to  highlight  to  the  medical  team  when  prescribed  anticoagulation 
medication is not administered. 
In  cases  where  a  patient  declines  critical  medication  e.g.,  VTE  prophylaxis,  anti-seizure 
medication, documentation must be very clear that the patient has capacity to understand the 
risks associated with this decision. 

Learning from this serious incident investigation has been shared across the organisation as 
part of the standard post investigation process to share learning across the group. 

 
 
 
 
 
 
 
 
 
 
 
  
  
  
 
 
 
  
 
 
  
 
  
  
  
  
 
  
  
 
 
  
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
  
   
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
    
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
   
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 2.  The Trust’s internal  investigator  recognised  that  a fail-safe should be put in place within the 
electronic records, to ensure escalation to the medical team where doses of prescribed anti-
coagulation are not administered. Such a measure could prevent similar deaths from occurring. 
It was considered that this measure could assist in preventing future deaths not just locally, but 
at a wider level. 

Our response: 
The  electronic  prescribing  and  medicines  administration  system  (ePMA)  currently  has 
functionality (all of which is accessible via Millennium®) to reduce harm associated with missed 
or late medication administration.  This includes visual aids in the form of a red tile if a dose is 
delayed by more than 2 hours.  This visual flag is available to all users.  Millenium training will 
be updated to reflect learning from this case to ensure that multi-professional teams know how 
to use the flag system to ensure critical medications are not omitted. 

Minimising  medication  dose  omissions  is  a  Trust  medicines  safety  improvement  priority 
supported by the trust Medicines  Safety  Committee.  A medicines  safety  dashboard is  being 
developed and will provide data on dose omission over a given period. The information will be 
used to track each ward's performance and to support quality improvement programmes across 
the Trust on dose omission. 

Actions  in  relation  to  this  letter and  evidence  of  completion  will  be  presented  at  the  Whipps  Cross 
Quality and Safety Committee and by exception to the Trust Quality Assurance Committee. 
The Trust deeply regrets that the serious incident investigation report and associated action plan did 
not  provide  HM  Coroner  and  the  patient’s  family  with  sufficient  assurance  around  the  actions 
implemented.  Arrangements will be made to share this letter with the patient’s family and an offer will 
be  extended  to  them  to  meet  with  senior  clinicians  to  discuss  any  questions,  concerns  or 
additional learning  and  improvement  that  the  Trust  should  implement  in  light  of the  death  Mr  John 
James.  If you have any further comments or questions, please do not hesitate to contact me. 

Yours sincerely 

Group Chief Medical Officer 
Barts Health NHS Trust

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