Prevention of Future Deaths reports · 2014

Lee Bonsall

Regulation 28 report to prevent future deaths, reference 2014-0044, written 31 Jan 2014. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report31 Jan 2014
Reference2014-0044
DeceasedLee Bonsall
CoronerJonathan Layton
Coroner areaCarmarthenshire & Pembrokeshire
CategoryService Personnel related deaths
Sourcejudiciary.uk record · original PDF
Responses published2

The report

Text extracted from the PDF text layer. Reproduced verbatim, including the scan's own layout.

REGULATION 28:  REPORT TO PREVENT FUTURE DEATHS  

REGULATION 28 REPORT TO PREVENT FUTURE DEATHS 

THIS REPORT IS BEING SENT TO: 

1.  Secretary of State for Health 

1 

CORONER 

I am Jonathan Mark Layton senior coroner, for the coroner area of Carmarthenshire and 
Pembrokeshire. 

2 

CORONER’S LEGAL POWERS 

I make this report under paragraph 7, Schedule 5, of the Coroners and Justice Act 2009 
and regulations 28 and 29 of the Coroners (Investigations) Regulations 2013. 

3 

INVESTIGATION and INQUEST 

On 6th March 2012 I commenced an investigation into the death of Lee Jay Bonsall then 
aged 23. The investigation concluded at the end of the inquest on 31st January 2014. 
The conclusion of the inquest was a narrative verdict namely that the deceased had 
suspended himself by a ligature from a bannister railing at his home address on 3rd 
March 2012 but the question of intent remains unclear.  The medical cause of death was 
asphyxia by hanging. 

4 

CIRCUMSTANCES OF THE DEATH 

(1)  Mr Bonsall had joined the Army at the age of 17 and had served in Afghanistan. 

During his tour of Afghanistan he witnessed the death of a close friend. 
(2)  An army psychiatrist subsequently deemed Mr Bonsall temperamentally 

unsuitable for service. He was discharged from the Army in September 2007. 
(3)  Mr Bonsall continued to suffer from depression.  He relocated to West Wales 

and registered with a surgery in 2010.  After an assessment he was prescribed 
citalopram.  He later renewed his prescription which his GP put on repeat 
prescription.  This is contrary to good practice guidelines.   

(4)  His GP considered counselling as an alternative to citalopram but did not refer 

Mr Bonsall for psychotherapy as there was a ten month waiting list. 

(5)  Mr Bonsall was found hanging from a bannister rail at his home address by his 

wife on 3rd March 2012. 

5 

CORONER’S CONCERNS 

During the course of the inquest the evidence revealed matters giving rise to concern. In 
my opinion there is a risk that future deaths will occur unless action is taken. In the 
circumstances it is my statutory duty to report to you. 

The MATTERS OF CONCERN are as follows.  –  

(1)   That citalopram was given on repeat prescription which is contrary to 

guidelines.  It may well be that awareness of these guidelines needs to be 
raised to ensure that GPs are aware that citalopram should not be given on 

1

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 (2)  The ten month waiting times for psychotherapy effectively means that this is not 
a viable alternative to   anti-depressant medication and it might well be that a 
review of these waiting times is appropriate. 

6 

ACTION SHOULD BE TAKEN 

In my opinion action should be taken to prevent future deaths and I believe you have the 
power to take such action.  

7 

YOUR RESPONSE 

You are under a duty to respond to this report within 56 days of the date of this report, 
namely by the 28th March 2014. I, the coroner, may extend the period. 

Your response must contain details of action taken or proposed to be taken, setting out 
the timetable for action. Otherwise you must explain why no action is proposed. 

8 

COPIES and PUBLICATION 

I have sent a copy of my report to the Chief Coroner and to the following Interested 
Persons: 

DAC Beachcroft LLP Portwall Place Portwall Lane Bristol BS99 7UD 
Defence Inquest Unit Directorate of Judicial Engagement Policy 2nd Floor Zone 5 IDL 
432 Ramilies Building Marlborough Lines Monxton Road Andover Hants SP11 8HJ 

I am also under a duty to send the Chief Coroner a copy of your response.  

The Chief Coroner may publish either or both in a complete or redacted or summary 
form. He may send a copy of this report to any person who he believes may find it useful 
or of interest. You may make representations to me, the coroner, at the time of your 
response, about the release or the publication of your response by the Chief Coroner. 

9 

31st January 2014                                             Signed: 

2

Responses

2 responses published against this report on judiciary.uk. A response is a body's written reply to the coroner's concerns; publication is at the discretion of the Chief Coroner's office, so an absent response does not mean nobody replied.

Response from Department of Health 1 (PDF)
From the Rt Hon Jeremy Hunt MP
Secretary of State for Health

|

@

| Department
of H ealth Richmond House
79 Whitehall
London
POCI_839556 SIIA 2NS
Tel: 020 7210 3000
Mr J Layton Mb-sofs@dh.gsi.gov.uk

Senior Coroner
Coronetr’s Office
Town Hall
Hamilton Terrace
Milford Haven

Pembrokeshire, SA73 3JW 31 MAR ants

Den babs,

Thank you for your letter following the inquest into the death of Lee Bonsall. In
your report you conclude that the medical cause of death was asphyxia by hanging.
I was very sorry to read of the events that led to the death of Mr Bonsall and wish to
extend my sincere sympathies to his family.

I understand Mr Bonsall had been in the army from the age of 17 and served in
Afghanistan. During his service he witnessed the death of a close friend. He was
discharged from the army in September 2007 after being found temperamentally
unsuitable for service. He continued to suffer depression, relocated to West Wales
and registered with a surgery there in 2010. His GP assessed him and prescribed
citalopram. He had a repeat prescription for this drug.

His GP considered counselling but did not refer Mr Bonsall for psychotherapy as
there was a 10 month waiting list in that area of Wales. Mr Bonsall was found
hanging by a ligature from a bannister rail at his home address on 3 March 2012.

You raise the following matters of concern:

e That citalopram was given on repeat prescription contrary to guidelines. You
suggest that awareness of these guidelines needs to be raised so that GPs are
aware that this drug should not be given on repeat prescription.

e The ten month waiting time for psychotherapy effectively means it is not a
viable alternative to anti-depressant medication. You suggest that a review of
these waiting times is appropriate.

As these tragic events took place in Wales and Mr Bonsall was under the care of the
Welsh health service, you will appreciate that I cannot comment on matters that are
the responsibility of the Welsh Government.

I therefore strongly recommend that your report is brought to the attention of the
Welsh Assembly. The Minister for Health and Social Services, Mark Drakeford
AM, can be contacted at the following address:

Welsh Government
5th Floor

Ty Hywel

Cardiff Bay

CF99 INA

However, it may be helpful if I explain the situation in England. In England there
are in general no national restrictions on which medicines can be prescribed under
repeat dispensing arrangements. The exception is scheduled drugs or controlled
drugs within the meaning of the Misuse of Drugs Act 1971. Citalopram does not fall
within this category.

Responsibility for prescribing, including repeat prescribing, rests with the prescriber
who has clinical responsibility for that particular aspect of a patient’s care. This
includes considering the suitability of prescribing a particular medicine for a
particular patient in light of individual circumstances. In England it is the
responsibility of local primary care organisations to ensure that adequate controls
are in place. They may therefore issue advice to GPs on repeat prescribing
mechanisms.

Comprehensive guidance is available to professionals about prescribing, including,
for example, repeat prescribing issues, prescribing for certain categories of patient
(including mental health) and prescribing of particular types of drugs, including
anti-depressants. The National Institute for Health and Care Excellence (NICE), the
General Medical Council and the British Medical Association have all produced
guidance that specifically addresses assessing the risk of prescribing a particular
medication for individuals at risk of self-harm. There is also specific product
information available for citalopram itself covered in the manufacturer’s Product
Information Leaflet (PIL) and the Summary of Product Characteristics.

Relevant extracts from these sources are attached at Annex A. However, you will
note that none of them specifically refers to repeat prescribing of citalopram.

O

epartment
of Health

Although your letter mentions guidelines, we cannot therefore establish exactly
what you are referring to. I would look into this matter further if you could supply
the information and if it falls within my remit.

Likewise, on waiting times, the situation in England is that access to services, and
the waiting times for those services, for people with mental health problems is
unfortunately sometimes longer than for physical health services. Ensuring that
mental health in England is treated equally with physical health means, for example,
ensuring that people do not experience excessively long waits for treatment.

The Department and NHS England are committed to ending this imbalance. We
believe that it is vital to develop and implement new access and waiting time
standards to have true parity of esteem. We are committed to providing access to
services and waiting times on a par with physical health.

NHS England is therefore developing options to improve access and waiting times
standards for mental health services. There will be a phased approach to
implementation of revised standards starting from April 2015.

Improving Access to Psychological Therapies (IAPT) is an NHS programme in
England which supports the frontline NHS in implementing NICE guidelines for
treating people suffering from depression and anxiety disorders. Despite the many
success stories, the clear focus and the good progress that has been made to date, as
IAPT expands new challenges emerge. The initial success of the programme in the
provision of services to the adult population has led to a rise in demand as more
people are offered this service.

I hope that this response is helpful and I am grateful to you for bringing the
circumstances of Mr Bonsall’s death to my attention.

we oe)
Ey
—

JEREMY HUNT

ais

| Department
| of Health

ANNEX A - PRESCRIBING GUIDANCE

1) Repeat prescribing

General Medical Council guidance, Good Practice in Prescribing and
Managing Medicines and Devices (2013)

http://www.gmc-uk.org/guidance/ethical_guidance/14316.asp

The section on repeat prescribing states:
Repeat prescribing and prescribing with repeats

55. You are responsible for any prescription you sign, including repeat
prescriptions for medicines initiated by colleagues, so you must make sure that
any repeat prescription you sign is safe and appropriate. You should consider
the benefits of prescribing with repeats to reduce the need for repeat
prescribing.

56. As with any prescription, you should agree with the patient what medicines
are appropriate and how their condition will be managed, including a date for
review. You should make clear why regular reviews are important and explain
to the patient what they should do if they:

a. suffer side effects or adverse reactions, or

b. stop taking the medicines before the agreed review date (or a set
number of repeats have been issued).

You must make clear records of these discussions and your reasons for repeat
prescribing.

57. You must be satisfied that procedures for prescribing with repeats and for
generating repeat prescriptions are secure and that:

a. the right patient is issued with the correct prescription

b. the correct dose is prescribed, particularly for patients whose dose
varies during the course of treatment

c. the patient’s condition is monitored, taking account of medicine usage
and effects

d. only staff who are competent to do so prepare repeat prescriptions for
authorisation

e. patients who need further examination or assessment are reviewed by
an appropriate healthcare professional

Jf. any changes to the patient’s medicines are critically reviewed and
quickly incorporated into their record.

58. At each review, you should confirm that the patient is taking their medicines
as directed, and check that the medicines are still needed, effective and
tolerated, This may be particularly important following a hospital stay, or
changes to medicines following a hospital or home visit. You should also
consider whether requests for repeat prescriptions received earlier or later than
expected may indicate poor adherence, leading to inadequate therapy or
adverse effects.

59. When you issue repeat prescriptions or prescribe with repeats, you should
make sure that procedures are in place to monitor whether the medicine is still
safe and necessary for the patient. You should keep a record of dispensers who
hold original repeat dispensing prescriptions so that you can contact them if
necessary.

Medical Protection Society
Repeat prescribing for GPs:

Care should be taken with any drug that is added to a repeat prescribing list.
However, some drugs lend themselves more readily to a repeat prescribing
approach, such as antihistamines, which require minimal levels of monitoring.
Drugs that are not suitable for routine repeat prescribing include hypnotics,
antidepressants and disease modifying agents, eg, methotrexate.

2) Use of anti-depressant drugs

The British National Formulary contains comprehensive advice about the use
and management of anti-depressant (AD) drugs and advises that:

“patients should be reviewed every 1-2 weeks at the start of antidepressant
treatment.”

Guidance on the use and dosage of the specific AD drug, Citalopram is also
included,

ee
Department
of Health

3) Prescribing of Citalopram

The Patient Information leaflet for Citalopram offers the following warnings and
advice about duration of treatment:

Warnings and precautions
Citalopram Tablets should be taken with caution if you:
e suffer from psychosis with depressive episodes, because the psychotic
symptoms may increase.

How long should you take Citalopram Tablets

Your doctor will decide on the duration of treatment.

An improvement in depressive symptoms can take at least 2 weeks after starting of
treatment. Treatment should be continued for at least 4-6 months. If you don’t
start to feel better after a couple of weeks, go back to your doctor who will advise
you.

The Summary of Product Characteristics (SPC) for Citalopram includes the
requirement for monitoring if suicide is a potential:

https://www.medicines.org.uk/emc/medicine/23861/SPC/Citalopram+20mg+Ta
blets/#POSOLOGY

Suicide/suicidal thoughts or clinical worsening

Depression is associated with an increased risk of suicidal thoughts, self harm and
suicide (suicide-related events). This risk persists until significant remission
occurs. As improvement may not occur during the first few weeks or more of
treatment, patients should be closely monitored until such improvement occurs. It
is general clinical experience that the risk of suicide may increase in the early
Stages of recovery.

Other psychiatric conditions for which citalopram is prescribed can also be
associated with an increased risk of suicide-related events. In addition, these
conditions may be co-morbid with major depressive disorder. The same
precautions observed when treating patients with major depressive disorder should
therefore be observed when treating patients with other psychiatric disorders.

Patients with a history of suicide-related events, or those exhibiting a significant
degree of suicidal ideation prior to commencement of treatment are known to be at

greater risk of suicidal thoughts or suicide attempts, and should receive careful
monitoring during treatment. A meta-analysis of placebo-controlled clinical trials
of antidepressant drugs in adult patients with psychiatric disorders showed an
increased risk of suicidal behaviour with antidepressants compared to placebo in
patients less than 25 years old.

Close supervision of patients and in particular those at high risk should
accompany drug therapy especially in early treatment and following dose changes.
Patients (and caregivers of patients) should be alerted about the need to monitor
for any clinical worsening, suicidal behaviour or thoughts and unusual changes in
behaviour and to seek medical advice immediately if these symptoms present.
Response from Department of Health (PDF)
From the Rt Hon Jeremy Hunt MP
Secretary of State for Health

Department
of H ea It h Richmond House
79 Whitehall
London
POC1_ 854254 SWIA 2NS
Tel: 020 7210 3000
Mr J Layton Mb-sofs@dh.gsi.gov.uk
Senior Coroner
Coroner’s Office
Town Hall
Hamilton Terrace
Milford Haven
Pembrokeshire, SA73 3JW ~FMAY Mth

Des be, lghs,

Thank you for your further letter of 3 April 2014 in response to mine of 31 March
2014 concerning the death of Lee Jay Bonsall.

Thank you also for clarifying the basis for your recommendation on the repeat
prescription of citalopram. As I said in my earlier response to you, there are no
national restrictions on the repeat prescribing of citalopram in England.

The National Institute for Health and Care Excellence’s clinical guidelines for the
treatment and management of depression in adults (CG90) state:

“1.5.2.6 For people started on antidepressants who are not considered to be at
increased risk of suicide, normally see them after 2 weeks. See them
regularly thereafter, for example at intervals of 2 to 4 weeks in the first
3 months, and then at longer intervals if response is good.

1.5.2.7 A person with depression started on antidepressants who is considered
to present an increased suicide risk or is younger than 30 years
(because of the potential increased prevalence of suicidal thoughts in
the early stages of antidepressant treatment for this group) should
normally be seen after 1 week and frequently thereafter as appropriate
until the risk is no longer considered clinically important.”

While I would agree that one might therefore expect antidepressant medicines in
most cases to be prescribed in accordance with these arrangements, NICE’s
guidelines are not rules and do not restrict the prescribing, including the repeat

prescribing, of such medicines. NICE’s clinical guidelines represent best practice
and are based on the available evidence and developed through wide consultation.
Prescribing and the management of individual cases, however, remain the clinical
responsibility of the doctor concerned.

NICE will be reviewing its guidelines on depression (CG90) in due course. I will
copy this reply to NICE, including your prescribing concerns, so they can consider
them for their next guideline review. I hope that this further response is helpful.

en saw
To Uw

JEREMY HUNT

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