Prevention of Future Deaths reports · 2017

Pamela Hands

Regulation 28 report to prevent future deaths, reference 2017-0373, written 18 Dec 2017. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report18 Dec 2017
Reference2017-0373
DeceasedPamela Hands
CoronerEmma Carlyon
Coroner areaCornwall and the Isles of Scilly
CategoryHospital Death (Clinical Procedures and medical management) related deaths
Sourcejudiciary.uk record · original PDF
Responses published1

The report

Text recovered by OCR from a scanned PDF. OCR is imperfect: check anything you rely on against the source PDF. Reproduced verbatim, including the scan's own layout.

REGULATION 28: REPORT TO PREVENT FUTURE DEATHS
Pamela Margaret Hands aka Horner

REGULATION 28 REPORT TO PREVENT FUTURE DEATHS
THIS REPORT IS BEING SENT TO:

The Royal College of Emergency Medicine, 7-9 Bream’s Building, Chancery Lane,
London, EC4A 1DT.

The Royal College of Surgeons (Orthopaedic), 35-43 Lincoln’s Inn Fields, London,
WC2A 3PE.

CORONER

|, Dr E Emma Carlyon am Senior Coroner for the coroner area of Cornwall and the Isles
of Scilly

CORONER’S LEGAL POWERS

| make this report under paragraph 7, Schedule 5, of the Coroners and Justice Act 2009
and regulations 28 and 29 of the Coroners (Investigations) Regulations 2013.

INVESTIGATION and INQUEST

On the 9" December 2015, I opened an investigation into the death of PAMELA
MARGARET HANDS otherwise known as PAMELA MARGARET HORNER. An
inquest was opened on 10 December and a full inquest hearing took place at
Truro Municipal Building, Truro between the 41" — 12" July 2017. The inquest
concluded that the cause of death was 1a Multi Organ Failure 1b Cardiac Arrest
(26.11.2015) 1c Effects of Relative Opiate Toxicity following administration of
Local Anaesthetic Nerve Block for a Periprosthetic fracture of the femur due to a
fall Il Coronary Artery Atherosclerosis.

A Narrative Conclusion was reached

“Pamela Margaret Hands died from multiple organ failure following a collapse in
the hospital Accident and Emergency Department on 26.11.15 due to the effects of
relative opiate toxicity following the administration of a local anesthetic for
necessary pain relief for a periprosthetic fracture due to a fall. The lack of
adequate patient observations from the time of administration of the Local
Anesthetic prevented the recognition of opioid toxicity and reversal of the opioid
side effects with an antidote and or medical intervention to avoid the cardiac
arrest”

CIRCUMSTANCES OF THE DEATH

Pamela Hands fell in the kitchen at her home address,

at just before 22.45 on 21° November 2015. She was transferred to
the Royal Cornwall Hospital by ambulance during which time she was
administered morphine sulphate for pain relief at 23.35 (5 mg) and 00.34 (2.5 mg).
She was diagnosed with a periprosthetic fracture of femur. She was givena
further dose of morphine sulphate between 1.20 - 30 am (10 mg). In order to assist

with pain relief a right fascia iliac block (40mls 2.5% bupivacaine) was
administered intravenously at 2.20 am with no issues. At the time of the
administration of the Local Anaesthetic and for 5-10 minutes after, there was no
evidence of opioid toxicity. She was not adequately observed from around 2.30
am. At 2.53 am she was found unresponsive on the bed, not breathing and with
no pulse. She was successfully resuscitated at 2.57 but despite this she never
recovered consciousness and despite medical support died on 1** December
2015. The effects of the opioid toxicity following the administration of the local
anesthetic nerve block for pain relief led to the respiratory and subsequence
cardiac arrest. Opioid and Fascia iliac blocks are recognized as being a standard
care pathway in the peri-operative management of patient with neck of femur
fractures. Observations after the administration of the fascia iliac block would on
balance have recognized the opioid toxicity allowing the antidote (Naloxone)
and/or other medical support to be administered and on balance the cardiac arrest
avoided.

CORONER’S CONCERNS

During the course of the inquest the evidence revealed matters giving rise to concern. In
my opinion there is a risk that future deaths will occur unless action is taken. In the
circumstances it is my statutory duty to report to you.

The MATTERS OF CONCERN are as follows. —

The Expert Consultant in Pain Medicine explained that after the fascia iliac block was
administered analgesia will occur over 10-15 minutes. As the patient obtains better
analgesia from the fascia iliac block, the opioids in the circulation would have a more
toxic effect than an analgesic effect. Pain is a potential arousal stimulus keeping the
patient awake and aware of their surroundings. Pain is also a respiratory stimulant.
There is an intimate link between the neurophysiology of pain and the respiratory
stimulant. It was recognised that removing a painful stimulus using a local anaesthetic
block can pre-dispose patients who have had opioids to respiratory depression. The risk
can be increased if the patient has other respiratory depressant risks such as alcohol
which can act synergistically with the opioid. In order to avoid this, the patient would
need to be observed during the first 30 minutes after the administration of the block to
reverse the effect of the opioid or support the respiration if required to avoid a cardiac
arrest and death.

At the time of the death were no National Guidelines to advise on the need to monitor
patients post procedure or application of the anaesthetic nerve block

At inquest it was clear from the evidence of the Clinical Director of Emergency Medicine
that in 2015 the effect of relative opioid toxicity following the administration of a local
anaesthetic nerve block for proximal femur fractures was not widely recognised within
Emergency Medicine. As there was an increase in the use of fascia iliac block in
conjunction with opioid analgesia in emergency medicine, this risk should be highlighted
to health professionals so that they were aware of the risk and the appropriate
guidelines put in place.

ACTION SHOULD BE TAKEN

In my opinion action should be taken to prevent future deaths and | believe you
[AND/OR your organisation] have the power to take such action.

To increase awareness to health professionals within your organisation or in general of
this risk so that the appropriate preventative measures, guidance and protocols are in
place within organisations to reduce the risk of respiratory depression, arrest or death
after the administration of fascia iliac block.

YOUR RESPONSE

You are under a duty to respond to this report within 56 days of the date of this report,
namely by the q2"" February 2018. |, the coroner, may extend the period.

Your response must contain details of action taken or proposed to be taken, setting out
the timetable for action. Otherwise you must explain why no action is proposed.

COPIES and PUBLICATION

| have sent.a copy of my report to the Chief Coroner and to the following Interested
Persons, AR of Watkins & Gunn Solicitors

representative for the Royal Cornwall Hospital Trust. | have also sent it to

representative of SWAST who may find it useful or of interest.

| am also under a duty to send the Chief Coroner a copy of your response.

The Chief Coroner may publish either or both in a complete or redacted or summary
form. He may send a copy of this report to any person who he believes may find it useful

or of interest. You may make representations to me, the coroner, at the time of your
response, about the release or the publication of your response by the Chief Coroner.

[DATE] [SIGNED BY CORONER]

18" December 2017 Suzebty. Gannra CoMyor

Responses

1 response published against this report on judiciary.uk. A response is a body's written reply to the coroner's concerns; publication is at the discretion of the Chief Coroner's office, so an absent response does not mean nobody replied.

Response from British Orthopaedic Association (PDF)
Your Ref: EEC/LJB  

13th February 2018  

Dr EE Carlyon 
Senior Coroner for the County of Cornwall and the Isles of Scilly, 
The New Lodge,  
Newquay Road,  
Penmount  
Truro TR4 9AA   
Email: cornwallcoroner@cornwall.gov.uk  

Dear Dr Carlyon, 

Regulation 28:  Report to prevent future deaths  
Re: Pamela Margaret Hands aka Horner  

Thank  you  for  your  letter  dated  the  18th  December,  received  by  us  in  January  and  discussed  at  our 
monthly Executive Board Meeting. I apologise for the late arrival of our response.  

The  BOA  recognises  the  importance  of  learning  from  past  events  and  understands  that  the  events  in 
question which are relevant to our associations occurred in December 2015.  

The BOA supports a multidisciplinary approach to the management of this group of vulnerable patients 
with  a  fracture  of  the  femoral  neck.  We  have  advocated  for  and  been  actively  involved  in  the 
development  of  a  prompt  MDT  approach  to  the  assessment  and  management  of  these  patients,  the 
development  of  dedicated  trauma  lists  for  patients  with  hip  fractures,  written  standards  for  the 
management of such fractures and the instigation of a National Hip Fracture Database that monitors the 
process for and outcome of these patients. We feel that the care of this group of patients has improved 
significantly over recent years. Outcomes are discussed regularly at our annual national meeting as well 
as amongst our Specialist Societies (such as the Orthopaedic Trauma Society – OTS). Relevant updates are 
cascaded to our membership via regular emails to the members of our association.  

We appreciate your recognition that a multidisciplinary team is involved in patient care but we note that 
you  have  only  contacted  the  BOA  and  the  Royal  College  of  Emergency  Medicine  with  respect  to  this 
incident.    It  is  often  the  Anaesthetists  and  the  Pain  Team  who  are  involved  in  the  local  guidelines  for 
management of pain in patients (including post procedural pain)  and the Nursing Staff who take prime 
responsibility for the monitoring of such patients following the administration of analgesic medication in 
any format. We feel that it important that your advice is distributed to all involved and we would like to 
suggest that you also seek input from the relevant bodies for nursing and anaesthesia, namely the RCN 
and the AAGBI. 

contd…/ 

 35-43 Lincoln’s Inn Fields London WC2A 3PE  
Tel: 020 7405 6507 Fax: 020 7831 2676 
  www.boa.ac.uk 

                                                             Registered Charity No. 1066994, Company limited by guarantee No. 3482958 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 On  our  part,  we  intend  that  our  BOAST  (BOA  Standards  for  Trauma)  document  that  covers  the 
management  of  hip  fractures  will  be  updated  to  reflect  and  emphasise  the  need  for  appropriate 
monitoring  of  all  patients  particularly  those  in  pain  pre  or  post  procedure.  This  document  is  due  for 
renewal within the next 12months.  



Should you feel that this letter does not cover all the issues that you are causing you concern, please do 
contact us again.  

Yours sincerely,  

Honorary Secretary BOA  

                                                             Registered Charity No. 1066994, Company limited by guarantee No. 3482958 

 35-43 Lincoln’s Inn Fields London WC2A 3PE  
Tel: 020 7405 6507 Fax: 020 7831 2676 
  www.boa.ac.uk

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