Prevention of Future Deaths reports · 2016

Rubana Pathan

Regulation 28 report to prevent future deaths, reference 2016-0113, written 18 Mar 2016. A coroner writes one of these when an inquest reveals a risk that could cause further deaths unless something changes.

Date of report18 Mar 2016
Reference2016-0113
DeceasedRubana Pathan
CoronerMary Hassell
Coroner areaInner North London
CategoryHospital Death (Clinical Procedures and medical management) related deaths
Organisation namedHomerton University Hospital NHS Trust
Sourcejudiciary.uk record · original PDF
Responses published1

The report

Text extracted from the PDF text layer. Reproduced verbatim, including the scan's own layout.

Regulation 28:  Prevention of Future Deaths report 

Rubana PATHAN (died 21.11.15) 

THIS REPORT IS BEING SENT TO: 

1. 

2. 

Medical Director 
Homerton University Hospital NHS Trust 
Homerton Row 
London  E9 6SR 

Medical Director 
Johnson & Johnson Medical Devices 
Pinewood Campus 
Nine Mile Ride 
Wokingham 
Berkshire 
RG40 3EW 

1 

CORONER 

I am:   Coroner ME Hassell 
           Senior Coroner  
           Inner North London 
           St Pancras Coroner’s Court 
           Camley Street 
           London  N1C 4PP 

2 

CORONER’S LEGAL POWERS 

I make this report under the Coroners and Justice Act 2009,  
paragraph 7, Schedule 5, and  
The Coroners (Investigations) Regulations 2013, 
regulations 28 and 29. 

3 

INVESTIGATION and INQUEST 

On  25  November  2015,  one  of  my  assistant  coroners,  Richard  Britain, 
commenced  an  investigation  into  the  death  of  Rubana  Pathan,  aged  40 
years. The investigation concluded at the end of the inquest earlier today. 
I made a determination as follows. 

1 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Rubana  Pathan  died  as  a  consequence  of  a  rare  but  recognised 
complication  of  medical  treatment,  being  a  staphylococcal  aureus 
infection of her breast implant wound.  (Breast reconstruction following a 
mastectomy undertaken to treat breast cancer.) 

4 

CIRCUMSTANCES OF THE DEATH 

Ms Pathan was admitted to Homerton University Hospital on Thursday, 5 
November  2015  and  was  immediately  recognised  to  be  potentially  very 
unwell.    Her  breast  reconstruction  wound  later  grew  staphylococcus 
aureus,  she  was  found  to  be  positive  for  the  TSST-1  gene,  and  was 
diagnosed with toxic shock syndrome.   

I recorded a medical cause of death of: 

1a  toxic shock syndrome 
1b  staphylococcus aureus infection 
1c  infected breast implant wound 

5 

CORONER’S CONCERNS 

During  the  course  of  the  inquest,  the  evidence  revealed  matters  giving 
rise to concern. In my opinion, there is a risk that future deaths will occur 
unless  action  is  taken.  In  the  circumstances,  it  is  my  statutory  duty  to 
report to you. 

The MATTERS OF CONCERN are as follows.  

Although Ms Pathan’s  MENTOR breast implant was suspected as being 
the cause of her sepsis and was removed on the evening of Saturday, 7 
November  2015,  her  surgeon  told  me  at  inquest  that  she  still  did  not 
believe  this  to  be  the  cause,  because  she  found  no  pus  or  localised 
redness. 

However, one of the treating microbiologists undertook a literature search 
after  Ms  Pathan’s  death  and  discovered  that  the  toxin  found  to  be 
responsible  for  her  illness  can  supress  signs  of  local  inflammation  such 
as the production of pus. 

Although  this  is  a  rare  occurrence,  it  seems  to  me  that  the  information 
could  usefully  be  disseminated  among  those  likely  to  be  caring  for 
patients who may be at risk of developing sepsis, both by the hospital and 
by the implant manufacturer. 

6 

ACTION SHOULD BE TAKEN 

2 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 In  my  opinion,  action  should  be  taken  to  prevent  future  deaths  and  I 
believe that you have the power to take such action.  

7 

YOUR RESPONSE 

You are under a duty to respond to this report within 56 days of the date 
of  this  report,  namely  by  23  May  2016.    I,  the  coroner,  may  extend  the 
period. 

Your  response  must  contain  details  of  action  taken  or  proposed  to  be 
taken,  setting  out  the  timetable  for  action.  Otherwise  you  must  explain 
why no action is proposed. 

8 

COPIES and PUBLICATION 

I have sent a copy of my report to the following. 

  HHJ Peter Thornton QC, the Chief Coroner of England & Wales 
  Professor Dame Sally Davies, Chief Medical Officer for England 
  Medicines and Healthcare Products Regulatory Agency 
 
 
 

 surgeon, Homerton University Hospital 
, microbiologist, Homerton University Hospital 

 husband of Rubana Pathan 

I  am  also  under  a  duty  to  send  the  Chief  Coroner  a  copy  of  your 
response.  

The Chief Coroner may publish either or both in a complete or redacted 
or summary form. He may send a copy of this report to any person who 
interest.  You  may  make 
he  believes  may 
representations to me, the Senior Coroner, at the time of your response, 
about  the  release  or  the  publication  of  your  response  by  the  Chief 
Coroner. 

it  useful  or  of 

find 

9 

DATE                                                   SIGNED BY SENIOR CORONER 

18.03.16 

3

Responses

1 response published against this report on judiciary.uk. A response is a body's written reply to the coroner's concerns; publication is at the discretion of the Chief Coroner's office, so an absent response does not mean nobody replied.

Response from Homerton University Hospital NHS Trust (PDF)
Homerton University Hospital 
Trust Offices 
Education Centre 
Homerton Row 
London 
E9 6SR 

Tel:  020 8510 7244 
www.homerton.nhs.uk 

25th May 2016 

Coroner Mary Hassell 
Senior Coroner 
Inner North London 
St Pancras Coroner’s Court 
Camley Street 
London, N1C 4PP 

By email to Coroner’s office: 

Dear Coroner Hassell, 

Re: Prevention of Future Deaths notice in relation to Staphylococcal Toxic Shock Syndrome 

Thank you for the email sent on 21st March, which contained a Prevention of Future Deaths notice in 
relation to the care of Mrs Rubana Pathan.  As you know, Mrs Pathan sadly died on 21st November 
2015 from Staphylococcus aureus Toxic Shock Syndrome following breast implant surgery.  In the 
PFD, you requested that we disseminate information about this particular and rare manifestation 
among our clinicians who are responsible for caring for patients who are at risk of developing sepsis.  
I am writing to confirm the actions undertaken in response by Homerton University Hospital. 

1.  I requested that 

, the microbiologist who gave evidence at the inquest, perform an 

evidence and literature search on surgical site Staphylococcal Toxic Shock Syndrome, with 
particular reference to suppression of pus formation resulting in benign-looking wounds. 

2.  I have highlighted the need to have a high index of suspicion for sepsis associated with 

Staphylococcal Toxic Shock Syndrome, and shared 
doctors in the Trust by email.  

 detailed literature search, with all 

3.  The case will be discussed in detail at a Hospital Grand Round, in order to ensure that the 
organisation learns as much as possible from this sad occurrence.  The Grand Round was 
scheduled to take place on 26th April, but unfortunately had to be postponed due to the junior 
doctors’ industrial action which took place that day, so will take place on 28th June.  

4.  The Trust has directed particular focus on encouraging early recognition and treatment of 

patients with sepsis, as part of its Improving Quality programme. In Quarter 4 of 2015-16 we 
were extremely pleased that all patients admitted to Homerton with severe sepsis received 
antibiotics within one hour. In 2016/17, we are broadening the focus of this programme, seeking 
to improve the recognition, escalation and treatment of patients on our in-patient wards with 
potential sepsis.  

Incorporating hospital and community health services, teaching and research 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 - 2 - 

I do hope that this provides assurance that we have taken appropriate action in response to the PFD 
notice.  Please do not hesitate to contact me if you require any further information. 

Yours sincerely, 

Medical Director 
Homerton University Hospital 

Incorporating hospital and community health services, teaching and research

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